We are delighted to announce Dr. Christine Orengo as a keynote speaker of the SCS Africa 2019!
Talk Title: "Looking for LUCA – and other evolutionary tales"
Christine Orengo is a computational biologist, whose core research has been the development ofrobust algorithms to capture relationships between protein structures, sequences and functions. She has built one of the most comprehensive protein classifications, CATH, used worldwide by tens ofthousands of biologists, and central to many pioneering structural and evolutionary studies.
CATH structural and functional data for hundreds of millions of proteins has enabled studies thatrevealed essential universal proteins and their biological roles, and extended characterisation of biological systems implicated in disease e.g. in cell division, cancer and ageing. CATH functional siteshave revealed protein residues implicated in enzyme efficiency and bacterial antibiotic resistance.
This data also identified genetic variations likely to be driving human diseases and the drugs that canbe repurposed to offset the pathogenic effects. Christine is a President Elect of the International Society of Computational Biology (ISCB). She is a Fellow of the Royal Society, a Fellow of the Royal Society of Biology an Elected member of EMBO since 2014, and a Fellow of ISCB. She is a founder of the European ELIXIR 3D-BioInfo Community inStructural Bioinformatics.